文章摘要
原发性肝细胞癌患者索拉菲尼服药依从性及与家庭关怀度的相关性
Sorafenib medication adherence and its correlation with family concern in patients with primary hepatocellular carcinoma
  
DOI:10.3969/j.issn.1007-8134.2019.04.023
中文关键词: 原发性肝细胞癌  索拉菲尼  服药依从性  家庭关怀度
英文关键词: hepatocellular carcinoma  sorafenib  medication adherence  family care
基金项目:
作者单位
刘春梓 中国人民解放军总医院第五医学中心介入科 
张晓宁 中国人民解放军总医院第五医学中心介入科 
王焕弟 中国人民解放军总医院第五医学中心介入科 
张飞飞 中国人民解放军总医院第五医学中心介入科 
于燕波 中国人民解放军总医院第五医学中心介入科 
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中文摘要:
      目的 探讨原发性肝细胞癌(hepatocellular carcinoma, HCC)患者索拉菲尼服药依从性现状,分析服药依从性与家庭关怀度的相关性。方法 应用Morisky服药依从性量表、家庭关怀度量表对我中心收治的218例HCC患者进行问卷调查,并对回收的215份有效问卷进行分析。结果 HCC患者索拉菲尼服药依从性平均得分为(6.67±2.51)分,家庭关怀度总平均分为(7.21±2.84)分;相关性分析显示服药时间、情感度、合作度、适应度等家庭关怀度指标对患者服药依从性均有影响。结论 HCC患者索拉菲尼服药依从性有待提高,医护人员可以通过鼓励延长服药时间、帮助改善家庭关怀度来提高患者服药依从性。
英文摘要:
      Objective To investigate the current status of sorafenib medication adherence in the patients with primary hepatocellular carcinoma (HCC) and analyze the correlation of medication adherence with family concern. Methods A total of 218 patients with HCC who were selected from our center were investigated and analyzed by questionnaires, including Morisky medication adherence measure and family care scale, and 215 effective questionnaires were collected and analyzed. Results The average score of sorafenib medication adherence in HCC patients was (6.67±2.51) points and the total average score of family care was (7.21±2.84) points. The correlation analysis showed that the duration of taking medicine, family care index such as affection, partnership and adaptation influenced the medication adherence. Conclusions Sorafenib medication adherence in HCC patients needs to be improved. Medical staff can improve the medication adherence by encouraging a prolonged medication duration and helping to improve family care.
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