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| 2010—2018年通辽市手足口病流行病学特征分析 |
| Epidemiological feature analysis of hand-foot-mouth disease in Tongliao City from 2010 to 2018 |
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| DOI：10.3969/j.issn.1007-8134.2020.06.016 |
| 中文关键词: 手足口病 流行病学特征 病原 预防控制 |
| 英文关键词: hand-foot-mouth disease epidemiological feature pathogen prevention and control |
| 基金项目:2016年内蒙古草原英才传染病防控创新人才团队 |
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| 中文摘要: |
| 目的 了解通辽市近9年手足口病流行特征和病原种类，为下一步制定防控措施提供科学依据。方法 采用描述性流行病学方法，阐述通辽市2010—2018年手足口病病例流行特征，对病原学监测结果进行统计分析。结果 2010—2018年全市共报告手足口病16 277例，其中重症309例，死亡6例，年平均发病率为57.54/10万。患者男女比例为1.43∶1，年龄以≤5岁为主（88.36%），散居和幼托儿童占发病总数的91.71%。2010—2018年期间，全市手足口病报告发病数居丙类传染病首位，发病高峰在6—7月。在958例实验室确诊病例中，EV-A71型病毒阳性占43.95%，其他EV阳性占37.99%，Cox A16型阳性占18.06%，不同年份EV-A71、Cox A16和其他EV阳性构成差异有统计学意义（χ2=220.118，P=0.005）。 结论 通辽市手足口病高发人群为年龄≤5岁儿童，发病有明显季节性，不同年份主要病原种类不同，EV-A71相对占优势。 |
| 英文摘要: |
| Objective To explore the epidemiological features and pathogen types of hand-foot-mouth disease in Tongliao City within the past 9 years, and provide scientific basis for subsequent formulation of prevention and control strategies. Methods Descriptive epidemiological methods were used to describe the epidemiological features of hand-foot-mouth disease cases reported in Tongliao City from 2010 to 2018. The results of pathogen monitoring were analyzed statistically. Results From 2010 to 2018, a total of 16 277 cases of hand-foot-mouth disease were reported in this city, including 309 severe cases and 6 deaths. The annual average incidence rate was 57.54/100 000. The ratio of male to female cases was 1.43∶1, the patient’s age was mainly ≤ 5 years old (88.36%), and the scattered and child care children accounted for 91.71% of the total number of cases. The number of reported cases of hand-foot-mouth disease in this city ranked first in Class C infectious diseases, and the peak incidence occurred in June and July. Among 958 laboratory confirmed patients, EV-A71 positive cases accounted for 43.95%, other enterovirus positive cases accounted for 37.99%, and Cox A16 positive cases accounted for 18.06%. There were statistically significant differences in EV-A71, Cox A16 and other enterovirus positive components in different years (χ2=220.118, P=0.005). Conclusions The high-risk population of hand-foot-mouth disease in Tongliao City is in children under 5 years old. The incidence has obvious seasonality. The main pathogens are different in different years. EV-A71 is relatively dominant. |
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