| [Abstract] Objective To understand the infection status and epidemic characteristic of HIV among voluntary blood donors in Kaifeng area, so as to provide reference for the recruitment of blood donors, the reduction of HIV transmission through blood transfusion and the safety of clinical blood transfusion. Methods A total of 539 015 samples of voluntary blood donors were tested for HIV preliminary screening by ELISA reagents from 2 different manufacturers and nucleic acid reagents, all positive samples were confirmed by HIV confirmatory laboratory of Kaifeng CDC. The infection status and epidemic characteristic of HIV in voluntary blood donors with different features were compared and analyzed. Results Among 539 015 samples of voluntary blood donors, 120 donors (2.23/10 000) were detected positive by HIV preliminary screening, and 53 donors (0.98/10 000) were confirmed as HIV positive. The total positives rates for HIV in male voluntary blood donors and all blood donors decreased from 2013 to 2020. After confirmation, the male donors (1.34/10 000), first-time donors (3.17/10 000), whole blood donors (1.05/10 000) and blood donors of registered residence in other places (2.39/10 000) had a significantly higher HIV positive rate in the samples than female donors (0.39/10 000), repeated donors (0.38/10 000), apheresis platelet donors (0.22/10 000) and blood donors of registered residence in this city (0.91/10 000), with statistically significant differences (P＜0.05). The HIV positive rate in donors of 26-35 years old was significantly higher than other age groups, with statistically significant difference (P＜0.05). Among 53 HIV-positive blood donors, only HIV infection was detected in 41 cases (77.63%) and HIV co-infection with other pathogens were detected in 12 cases (22.64%). Conclusions The HIV positive rate among voluntary blood donors in Kaifeng area shows a declining trend since 2013, HIV infection is dominantly prevalent in young males, whole blood donors, first-time donors, donors with lower academic qualifications, company workers and blood donors of registered residence in other places. Strengthening the inquiry before blood donation and establishing a low-risk and stable blood donation population can reduce/avoid the transmission risk of HIV through blood transfusion. ?? ? 耀??MS Mincho ?Ё斯??????? ??? ??? ? 蘀??宋体 ?????Ё斯??????? ??? 耀?children. |