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| 新型冠状病毒肺炎心脏相关评估指标特征分析 |
| Analysis on characteristics of heart related assessment index in COVID-19 |
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| DOI：10.3969/j.issn.1007-8134.2021.02.008 |
| 中文关键词: 新型冠状病毒肺炎 心肌损伤标志物 心电图 危重型 重型 普通型 年龄 基础疾病 |
| 英文关键词: COVID-19 myocardial injury markers electrocardiogram critical severe common age underlying disease |
| 基金项目:广东省防控新型冠状病毒科技公关应急专项（2020B111105001） |
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| 中文摘要: |
| 目的 分析新型冠状病毒肺炎（新冠肺炎）患者心脏相关评估指标，为新冠肺炎患者救治及预后评估提供依据。方法 采用回顾性研究方法，以2020年1月21日—2月20日期间我院收治的95例新冠肺炎患者作为研究对象，根据临床症状将患者分为危重型组（14例），重型组（40例）和普通型组（41例），对比分析3组患者心肌损伤标志物和心电图。结果 危重型组和重型组年龄分别为（64.2±13.2）岁和（60.0±13.0）岁，均显著高于普通型组的（50.0±16.5）岁（P均＜0.05）。重型组AST、LDH及危重型组CK升高率均高于普通型组（P均＜0.05），其中LDH绝大多数为轻度升高。心电图异常以T波改变为主，未见恶性心律失常。结论 新冠肺炎患者心脏指标异常多见于危重型组和重型组，与年龄和基础疾病相关，LDH升高最多见，但程度较轻，心电图异常以T波改变为主。 |
| 英文摘要: |
| Objective To analyze heart related assessment index in patients with COVID-19 and provide evidence for evaluating prognosis and treating patients with COVID-19. Methods From January 21st to February 20th 2020, a total of 95 patients with COVID-19 admitted to our hospital were included in this retrospective study. The included patients were divided into 3 groups according to their clinical symptoms: critical group (n=14), severe group (n=40) and common group (n=41). Myocardial injury markers and electrocardiogram of the 3 groups were compared and analyzed. Results The age of critical group and severe group was (64.2±13.2) years and (60.0±13.0) years, which was significantly higher than that in common group (50.0±16.5) years (P＜0.05). Compared with the common group, the proportion of elevated AST and LDH in severe group and the proportion of elevated CK in critical group increased (P＜0.05). In most of cases, LDH elevated slightly. The abnormal electrocardiogram was mainly T wave change, and no malignant arrhythmia was found. Conclusions Patients with critical and severe COVID-19 are susceptible to abnormal cardiac indicators, which are related to age and underlying diseases. Elevated LDH is the most frequently observed, but to a lesser degree. The abnormal electrocardiogram is mainly T wave change. |
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