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| 肝脏原发性神经内分泌肿瘤研究进展 |
| Research progress on primary hepatic neuroendocrine tumors |
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| DOI：10.3969/j.issn.1007-8134.2021.04.016 |
| 中文关键词: 神经内分泌肿瘤 肝脏原发性神经内分泌肿瘤 诊断 治疗 临床特点 病理特征 |
| 英文关键词: neuroendocrine tumor primary hepatic neuroendocrine tumor diagnosis treatment clinical feature pathological feature |
| 基金项目:国家高技术研究发展计划（2015AA020924） |
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| 中文摘要: |
| 肝脏原发性神经内分泌肿瘤（primary hepatic neuroendocrine tumors, PHNETs）是一组极其罕见、分化良好的低度恶性肿瘤，其临床特征、实验室检查与影像学结果等缺乏特异性表现。因此，需要在病理诊断的基础上排除其他部位神经内分泌肿瘤肝转移的情况，才能确诊该疾病。目前，PHNETs主要采用以手术切除为主的综合治疗方法。本文收集并整理了206例国内外PHNETs的病例报告及相关文献，对PHNETs的起源、临床特点、病理特征、临床诊治进展总结分析，以期为PHNETs的全面认识和临床诊疗提供重要依据。 |
| 英文摘要: |
| Primary hepatic neuroendocrine tumors (PHNETs) are extremely rare and well differentiating low-grade malignancy tumor, and their clinical features, laboratory and imaging examinations lack specific manifestations. Therefore, their confirmed diagnosis need to be based on pathological diagnosis and exclude neuroendocrine tumors liver metastases at other sites. At present, the treatment of PHNETs is a comprehensive treatment method based on surgical resection. This review collects and sorts out 206 PHNETs case reports and related literatures in China and abroad, summarizes and analyzes the cause, clinical and pathological characteristics, clinical diagnosis and treatment of PHNETs, so as to provide significant evidence for the comprehensive understanding and clinical diagnosis and treatment of PHNETs. |
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