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| 49例艾滋病合并马尔尼菲篮状菌病患者的临床特征分析 |
| Clinical characteristics analysis of 49 AIDS patients with talaromycosis marneffei |
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| DOI：10.3969/j.issn.1007-8134.2021.05.009 |
| 中文关键词: 艾滋病 马尔尼菲篮状菌病 临床特征分析 |
| 英文关键词: AIDS talaromycosis marneffei clinical characteristics analysis |
| 基金项目:“十三五”国家科技重大专项（2018ZX10302103-001） |
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| 中文摘要: |
| 目的 探讨艾滋病合并马尔尼菲篮状菌病的临床特征。方法 回顾性分析2012年1月—2021年2月我院收治的49例艾滋病合并马尔尼菲篮状菌病患者的一般资料及临床资料。结果 患者主要以发热、皮疹、咳嗽咳痰、脾大、淋巴结肿大等为临床特征，可出现白细胞、血小板减少，贫血，肝功能受损，ESR增快，CRP及降钙素原水平升高，浆膜腔积液，且多同时合并其他机会性感染。结论 艾滋病免疫功能低下的患者，应尽早获得马尔尼菲篮状菌阳性病原学结果，避免误诊及延误治疗。 |
| 英文摘要: |
| Objective To explore the clinical characteristics of AIDS with talaromycosis marneffei. Methods A retrospective study was conducted on the general information clinical data of 49 AIDS with talaromycosis marneffei from January 2012 to February 2021. Results The main clinical characteristics of these patients were fever, rash, cough and expectoration, splenomegaly, lymphadenectasis. They appeared leucocytopenia, thrombocytopenia, anemia, impaired liver function, rapid ESR, elevated CRP with procalcitonin and dropsy of serous cavity. Most of them were accompanied by other opportunistic infections. Conclusions For AIDS patients with immunocompromice, it is necessary to obtain the early positive etiological results of Talaromyces marneffei, so as to avoid misdiagnosis and belated treatment. |
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