| To explore the changes of serum inflammatory factors and the percentage of peripheral blood T cell subsets in patients with lung bacterial infection after pulmonary contusion. Methods One hundred and four patients with lung contusion who were treated in our hospital from July 2015 to July 2018 were selected as the research objects. According to whether bacterial infectious pneumonia occurred during treatment, they were divided into infection group (n=42) and non-infectious group (n=62). The levels of serum inflammatory factors and peripheral blood T cell percentage subgroups before and after treatment were detected and compared between 2 groups. Results Compared with the non-infected group, the levels of serum procalcitonin, C-reactive protein and IL-6 before treatment in the infected group were higher, the percentage of CD3+ T cells, the percentage of CD4+ T cells, and the percentage of CD4+ T cells/CD8+ T. The percentage of cells was low and the difference was statistically significant (P＜0.05); compared with before treatment, the levels of serum procalcitonin, C-reactive protein, and IL-6 in 2 groups decreased after treatment, and the differences were both It was statistically significant (P＜0.05). Compared with before treatment, the percentage of CD3+ T cells, the percentage of CD4+ T cells and the ratio of CD4+/CD8+ T cells in the infected group increased after treatment. The difference was significant (P＜0.05) and was lower than the non-infected group . Conclusions Pulmonary contusion patients with pulmonary bacterial infection have higher levels of inflammatory factors, more intense inflammatory response, significantly lower levels of peripheral blood T cell percentage subgroups, and severely impaired immunity of patients. Clinical diagnosis and treatment should be paid more attention to. |