文章摘要
  
DOI:
中文关键词: 发热伴血小板减少综合征病毒  细胞因子风暴  天然免疫  T细胞  B细胞
英文关键词: severe fever with thrombocytopenia syndrome virus  cytokine storm  innate immunity  T cells  B cells
基金项目:
作者单位
何 洪 北京中医药大学东直门医院检验科 
许 文 解放军总医院第五医学中心感染病医学部 
陈威巍 解放军总医院第五医学中心感染病医学部 
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中文摘要:
      发热伴血小板减少综合征病毒感染可引起发热伴血小板减少综合征,是一种以蜱为主要传播媒介的新发突发传染病,主要在我国农村、山林等地区流行,病死率可达5%~30%,对我国农业生产造成严重影响。免疫系统功能异常在病毒感染性疾病的发生发展中具有重要的作用。本文对发热伴血小板减少综合征病毒感染中的免疫学功能异常相关的研究进行了综述,以期增进相关研究人员和医务人员对本病的认识,促进机制研究和诊治新技术的研发。
英文摘要:
      Severe fever with thrombocytopenia syndrome, caused by severe fever with thrombocytopenia syndrome virus infection, is a new emerging infectious disease with ticks as the main vector. This disease is prevalent in rural or forest areas in China, accounting for 5%-30% fatality rate. Abnormal immune system function plays an important role in the occurrence and development of viral infectious diseases. This article reviews the research related to abnormal immunological function in severe fever with thrombocytopenia syndrome virus infection, thus enhancing the understanding of related researchers and medical staff for this disease, and promoting mechanism research and development of new technology for diagnosis and therapies.
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