文章摘要
49例HIV感染孕产妇流行病学特征调查
Investigation of epidemiological characteristics of 49 HIV-infected pregnant women
  
DOI:10.3969/j.issn.1007-8134.2022.04.010
中文关键词: HIV感染  流行病学特征  健康教育  母婴传播  传播途径  暴露风险  孕产妇  HIV RNA载量
英文关键词: HIV-infected  epidemiological characteristic  health education  mother-to-child transmission  transmission route  exposure risk  pregnant women  HIV RNA load
基金项目:深圳市科创委基金(JCYJ20210324131605015)
作者单位
李晓玲 深圳市第三人民医院院感防保科 
黄?婷 深圳市第三人民医院院感防保科 
邱谷香 深圳市第三人民医院院感防保科 
黄海英 深圳市第三人民医院院感防保科 
刘晓宁 深圳市第三人民医院院感防保科 
何?云 深圳市第三人民医院院感防保科 
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中文摘要:
      [摘要] 目的 分析深圳地区HIV感染孕产妇流行病学特征,为流动人口较多地区预防HIV母婴传播政策制定提供依据。方法 收集并分析2019年1月1日—2021年12月31日在深圳市第三人民医院接受HIV母婴传播阻断管理的49例孕产妇的人口学及临床资料。结果 49例HIV感染孕产妇平均年龄为(25.90±5.18)岁,89.8%(44/49)文化程度在大学水平以下,59.2%(29/49)为深圳户籍,40.8%(20/49)为非深圳户籍或流动人口。以被动诊断发现HIV感染为主,约占75.5%(37/49),主动诊断发现HIV感染约占24.5%(12/49)。38.8%(19/49)为性接触传播感染,59.2%(29/49)传播途径未明。49例HIV感染孕产妇产后全部接受抗反转录病毒治疗。配偶/性伴侣HIV抗体或核酸检测率为93.9%(46/49),其中32.6%(15/46)确诊HIV感染。100%(49/49)儿童在出生后6 h内使用阻断药物、进行早诊断及人工喂养。6.1%(3/49)儿童为高暴露风险儿童。结论 HIV感染孕产妇早诊断率低导致儿童暴露风险增高,加强孕产妇健康教育和管理可能是解决目前HIV母婴传播的重要环节。
英文摘要:
      [Abstract]?Objective To analyze epidemiological characteristics of HIV-infected pregnant women in Shenzhen and to provide policy formulation for the prevention of mother-to-child transmission of HIV in areas with large float populations. Methods?The demographic and clinical data of 49 pregnant women who received HIV mother-to-child transmission block management in Shenzhen Third People's Hospital from January 1, 2019, to December 31, 2021, were collected and analyzed. Results?Forty-nine HIV-infected pregnant women were involved, the average age was (25.90±5.18) years old, 89.8% (44/49) were below college level, 59.2% (29/49) are registered residents, and 40.8% (20/49) are non-registered residents or floating population. HIV infection was mainly found in passive diagnosis, accounting for about 75.5% (37/49), and HIV infection was found in active diagnosis, accounting for about 24.5% (12/49). 38.8% (19/49) were transmitted through sexual contact, and 59.2% (29/49) by an unknown route of transmission. All 49 HIV-infected women received ART after delivery. 93.9% (46/49) of their spouses or sexual partners were tested for HIV and 32.6% (15/46) were diagnosed with HIV infection. All of their children were given blocking drugs within 6 hours after birth, early diagnosis, and artificial feeding. 6.1% (3/49) of children were born with high-risk HIV exposure. Conclusions?The low rate of early diagnosis in HIV-infected pregnant women leads to a higher risk of exposure for their infants. Strengthening health education and management of HIV-infected pregnant women is an important part of solving the problem of mother-to-child transmission of HIV.
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