Coxiella burnetii is the pathogen that causes Q fever, which is a zoonotic disease, which is rarely reported in my country. Q fever can present with a variety of clinical syndromes, the most common and most severe nonspecific manifestation is blood culture-negative endocarditis, and the course of the patient"s disease is severe and fatal without prompt recognition and appropriate antimicrobial therapy. This article introduces a case of endocarditis with negative blood culture, which was diagnosed by gene sequencing, and based on its epidemiology, physical signs, laboratory diagnosis and treatment, to help Chinese clinicians in the diagnosis and treatment of Q fever infected heart Endocarditis provides a certain clinical reference. |