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| 一例播散性卡介菌报告 |
| A report of a Disseminated Bacillus Calmette-Guerin infection |
| 投稿时间：2024-01-16 修订日期：2024-04-24 |
| DOI： |
| 中文关键词: 卡介苗 播散性卡介菌病 不良反应 |
| 英文关键词: BCG disseminated BCG disease adverse reaction |
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| 中文摘要: |
| [摘要]卡介苗是一种预防结核病的减毒活疫苗，在健康新生儿中出生时即接种。轻度不良反应为接种2～3天后，局部皮肤出现发红，触之无硬结，数日 后自行消退。播散性卡介菌病是最严重不良反应，临床表现主要为接种部位红肿、破溃和溢脓，全身多发性淋巴结肿大、皮肤包块形成和肺部病变，也可累及肝脏、脾脏和骨骼[[[] 中华医学会结核病学分会，中国防痨协会学校与儿童结核病防治专业分会. 卡介苗不良反应临床处理指南[J]. 中国防痨杂志,2021,43(6):532-538. DOI: 10.3969/j.issn.1000-6621.2021.06.002.]]。该病致死率高，早期诊断及治疗方法的选择仍是难题，现就我科诊治的一例临床诊断的播散性卡介菌病患儿的过程及相关文献复习总结如下，希望能给相应专业的临床医师提供一定帮助。 |
| 英文摘要: |
| [Abstract] Bacillus Calmette-Guérin (BCG) is a live attenuated vaccine against tuberculosis that is given at birth in healthy newborns. Mild adverse reactions were local skin redness 2-3 days after inoculation, no induration after contact, and resolved after a few days. Disseminated BCG is the most serious adverse reaction. The main clinical manifestations are redness, swelling, ulceration and discharge at the inoculation site, systemic lymph node enlargement, skin mass formation and lung lesions, and may also involve the liver, spleen and bone. The fatality rate of this disease is high, and the choice of early diagnosis and treatment is still a difficult problem. The process and related literature review of a clinically diagnosed child with disseminated BCG in our department are summarized as follows, hoping to provide some help to clinicians in the corresponding profession. |
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