| Objective To investigate the risk factors of hepatitis B cirrhosis complicated with liver cancer and provide evidence for clinical diagnosis and treatment. Methods Data of 238 patients with hepatitis B cirrhosis admitted to our hospital from January 2016 to December 2018 were analyzed retrospectively. The included patients were divided into 2 groups according to the presence/absence of hepatocellular carcinoma, namely liver cancer group (120 cases) and non-liver cancer group (118 cases). The risk factors of hepatitis B cirrhosis complicated with hepatocellular carcinoma were analyzed. Results The percentages of male, family history of liver cancer, family history of other tumors, diabetes history, long-term smoking history, long-term drinking history, positive HBV and antiviral treatment in the liver cancer group were higher than those in the control group (P＜0.05). Logistic regression analysis showed that the history of diabetes, long-term drinking history, long-term smoking history, positive HBV and no antiviral treatment were risk factors for liver cancer in patients with hepatitis B cirrhosis. Conclusions Male patients are more prone to hepatitis B cirrhosis than female patients. The risk factors for liver cancer in patients with hepatitis B cirrhosis include the history of diabetes, absence of antiviral treatment, long-term smoking history, long-term drinking history and positive HBV. |