Objective To analyze the epidemiological characteristics, clinical manifestations, treatment and prognosis of 308 patients with dengue fever in Cenxi City of Guangxi, so as to provide references for the prevention and treatment of dengue fever. Methods The clinical information of 308 patients diagnosed as dengue fever in Cenxi People’s Hospital from September 1 to October 31, 2020 was collected. The 308 patients were divided into elderly group (≥60 years old) and non-elderly group (<60 years old) according to their age. The demographic data, epidemiological data, clinical characteristics, laboratory and imaging examination results, treatment and prognosis of patients were collected, and the epidemiological characteristics of patients in the 2 groups were analyzed and compared. Results The dengue fever was prevalent in the middle-aged and young people. The main clinical symptoms of dengue fever included fever, anorexia, rash, muscular soreness and pruritus. The incidences of rash and pruritus symptoms in non-elderly group were 81.51% and 49.81%, respectively, which were significantly higher than those in elderly group (P<0.05). There was no significant difference in the positive rate of etiological detection results between the elderly group and the non-elderly group (P>0.05). The incidences of reduced PLT and ALB in the elderly group were 32.56% and 81.40%, respectively, which were significantly higher than those in the non-elderly group (P<0.05). There was no significant difference in the abnormal rates of other blood indicators between the 2 groups (P>0.05). Chest CT or chest radiograph of 25 patients showed different degrees of abnormal changes. Conclusions The infection source for the first cases in dengue fever outbreak remains unclear. The majority of the patients were young and middle-aged. The main clinical symptoms include fever, anorexia, rash, muscular soreness and pruritus. At present, the pathogenesis of dengue fever is not completely clear. There is no effective vaccine in clinical practice to prevent dengue fever. The prevention measure of dengue fever is mainly the cut-off the infection source. Early diagnosis, early isolation and early treatment are the key measures to treat this disease. |